PSSD or Post-SSRI Sexual Dysfunction in Metro-Phoenix

PSSD, or Post-SSRI Sexual Dysfunction, is a condition where sexual dysfunction persists long after a person has stopped taking Selective Serotonin Reuptake Inhibitors (SSRIs). Symptoms can include genital numbness, a decrease in sexual desire, difficulty with arousal or orgasm, and erectile dysfunction, and may last for months, years, or indefinitely. Diagnosis involves ruling out other causes of sexual problems and confirming a history of SSRI use. Treatment is challenging and currently lacks definitive solutions, requiring consultation with a healthcare professional to explore potential strategies and advocate for a personalized treatment plan. 

What are the symptoms of PSSD?

PSSD can manifest in a variety of ways, with common symptoms including: 

  • Genital anesthesia: or numbness in the genital area
  • Diminished sexual desire: (loss of libido)
  • Weak or pleasureless orgasms
  • Difficulty with arousal: and erectile dysfunction
  • Vaginal lubrication issues: in women
  • Nipple insensitivity: in women

What causes PSSD?

The exact cause of PSSD is not fully understood, but several theories suggest potential mechanisms, including: 

  • Epigenetic gene expression: changes
  • Neurotransmitter imbalances, particularly dopamine and serotonin
  • Serotonin neurotoxicity
  • Hormonal changes: and altered sex steroid levels
  • Changes in the gut microbiome

How is PSSD diagnosed?

A diagnosis of PSSD involves: 

  1. Eliminating other potential causes: of the sexual problems.
  2. Confirming a history: of past use of SSRI medications.

What are the treatment options for PSSD?

Treatment for PSSD is a significant challenge with no definitive solutions. Strategies may involve a multimodal approach, including: 

  • Consultation with a qualified healthcare professional .
  • Cognitive behavioral therapy (CBT): to address psychological factors.
  • Pharmacological interventions, such as dopaminergic medications, though their efficacy in PSSD is limited.
  • Advocating for personalized treatment plans: to manage symptoms.

If you think you may be struggling with PSSD, contact me through this link or by calling or by calling (602) 492-6507